Unless you are going to leave the PC on 24 hours a day with automatic send and receive during your absence, out of office replies on a pop3 account are a waste of time. You should investigate instead whether you can set such a message at the server. Many ISPs do offer this facility. For those that don't, you could route your mail through a gmail account (which will also take care of spam filtering).

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Graham Mayor - MS MVP (Word) (2002-2019)
Visit my web site for more programming tips and ready made processes www.gmayor.com