Presuming Presentation.pptm is open and the sub exists that depending on what you mean by command line that should work.

It's probably not the way to do it though. Why not create a ppam AddIn that creates a ribbon button to run the code on any active presentation?

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Thank you for your response.

My apologies I should have clarified that it I don't want the file to open. It would be nice to have it run in the background somehow because when the file opens it prompts the user to update the links or not before the macro runs. For Excel an example is:

objExcel.Application.Run "Presentation.pptm!UpdateLinks2Local"

I would like that (above) functionality but for PowerPoint.

My main goal is that a user can run this unattended, as it takes 3-5 minutes to update everything. The intention to be able to run the script to update the PPT just before a presentation to a client.