I can't see any way to do that without macros and you cannot associate a macro with an e-mail message, as it would be a wide open invitation to those with malicious intent.

The nearest to your request is covered on my web site at http://www.gmayor.com/EMail_Response.htm, however, that only gets the users back as far as your web site, where you could no doubt process the responses.

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Graham Mayor - MS MVP (Word) (2002-2019)
Visit my web site for more programming tips and ready made processes www.gmayor.com