So, everything were working fine until Win10 (Home GR 64bit) force-updated the latest 620M Nvidia Drivers (390.77) which totally rendered the installed Office Pro Plus 2016 unusable. None of the apps can open, not even in safe mode. I tried online repair, registry fixes, disk check, disk optimization, complete uninstall and reinstall of Office, clean uninstall and reinstall of the Nvidia drivers, system restore to the previous state of the update. Nothing worked, i keep getting the same message. Office can't open, try in safe mode, can't open in safe mode either, close program. The only action left is format the Drive but i am starting to think that it still may not be fixed. The most strange thing is that i didn't find anyone else with this problem... am i the first?