object variable or with block variable not set

[MJP143]

Hello, I get the following error when pressing the "save" icon on the toolbar in Excel: object variable or with block variable not set. I am only able to save a document by hitting "Control S" or going to "file/save". This all started when I got a new computer a month ago. I am not very techy and have gone to our IT department 6 times and all they do is reset/restore my profile, which is almost more annoying than not being able to save because I have to redo all my settings AND it never solves my Excel problem. I can't be the first person out there to have this happen Please help! I will take any advice I get here and ask my company IT department to try it.