Option Explicit
Sub RemoveLineBreaks()
  'Looks at row 1 to find 2 columns and then runs a script to remove
  'all line breaks from the range
  Dim CheckRow As Long, TotalRows As Long
  Dim BadData As Variant, x As Integer
  Dim ICol As Integer, NCol As Integer, CheckCol As Integer
  Dim CheckNstring As String, CheckIstring As String, CheckColString As String
  Dim NewNstring As String, NewIstring As String
  
  'Set the variables and find the needed columns
  
    TotalRows = Range("A50000").End(xlUp).Row
    On Error Resume Next
    ICol = Range("1:1").Find("Items", LookAt:=xlWhole).Column
    NCol = Range("1:1").Find("No.", LookAt:=xlWhole).Column
    'Check if column numbers were found
    If ICol = 0 Then
      MsgBox ("Cannot find the term 'Items' in Row 1." & vbLf & "Please update and try again.")
      End
    End If
    If NCol = 0 Then
      MsgBox ("Cannot find the term 'No.' in Row 1." & vbLf & "Please update and try again.")
      End
    End If
    
    On Error GoTo 0 'Reset error handling
    BadData = Array(vbCr, vbLf, vbCrLf, Chr(10), Chr(13))
    
    
    'Fix the column headers
    For CheckCol = 1 To 255
      CheckColString = Cells(1, CheckCol).Value
      For x = 0 To UBound(BadData)
        CheckColString = WorksheetFunction.Substitute(CheckColString, BadData(x), " ")
      Next x
      Cells(1, CheckCol).Value = Trim(CheckColString)
      If Cells(1, CheckCol).Value = "" Then Exit For 'Exit loop when there is no more data
      CheckColString = ""
    Next CheckCol

    'Check the 2 columns
    For CheckRow = 2 To TotalRows
      CheckIstring = Cells(CheckRow, ICol).Value
      CheckNstring = Cells(CheckRow, NCol).Value
      For x = 0 To UBound(BadData)
        CheckIstring = WorksheetFunction.Substitute(CheckIstring, BadData(x), ",")
        CheckNstring = WorksheetFunction.Substitute(CheckNstring, BadData(x), ",")
      Next x
      Cells(CheckRow, ICol).Value = CheckIstring
      Cells(CheckRow, NCol).Value = CheckNstring
      
      'Clean up Vars
      CheckIstring = ""
      CheckNstring = ""
      Debug.Print TotalRows - CheckRow & " Records Left."
    Next CheckRow
    
    MsgBox "Complete"
End Sub