I have run Outlook in Safe mode and it does still happen. Running through that KB
https://support.microsoft.com/en-us/kb/2695805 article I did as it suggested. No Add-ins, still happens. Outlook in non-cached and cached mode, still happens either way.
Oddly enough though, when i put it in safe mode it seemed ok for a few days, but then it started up again this week.
Running latest version of Outlook 2010, all SP's and updates applied. Get the same issue on a pc with no PST files as one with PST files attached.
Running a Gen 3 SSD. The only Add-ins that I have on all my domain pc's are Exchange Add-in and Kaspersky add-in. But this issue predates Kaspersky.
I have also tried re-creating a new Mail profile with no joy.
Any other suggestions?