I'm not familiar with PDF editing, though each page in a PDF is a stand-alone unit and changing font sizes, etc on one page won't cause any text reflowing to/from other pages.
I'm not sure why you'd want to increase the font size if you want to save paper (I'd have thought you'd want to decrease it). However, you can tell Acrobat to print multiple pages per sheet.
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Cheers,
Paul Edstein
[Fmr MS MVP - Word]
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