Yes, it's possible. It's essentially a matter of adding the requisite code to a Document_Open sub. For example:
Code:
With ActiveDocument.Content.Find
.ClearFormatting
.Replacement.ClearFormatting
.Text = "monitor"
.Replacement.Text = "review"
.Forward = True
.Wrap = wdFindContinue
.Format = False
.MatchCase = False
.MatchWholeWord = True
.MatchWildcards = False
.MatchSoundsLike = False
.MatchAllWordForms = False
.Execute Replace:=wdReplaceAll
End With