right, the letter variation is yet another reason that this guideline is simply a poor choice. (incidentally, I just measured about twenty letters on a sample page and most of them are closer to 1/12th of an inch, especially lowercase letters other than i or l. Many capital letters are wider of course).
I think the formatting guide I'm dealing with was created a long time ago and it just was never really thought through since then. I'm developing a template that I'm going to recommend to them that discards the two-space setting and other problematic issues.

for now though, unfortunately, I have to play trial and error with them.