Hi,
Here's one way.
In the name manager (on the formulas tab), define a name called Letters which refers to this:
={"A","F","T"}
Then, in the conditional formatting, create a new rule which uses a formula to determine which cells to format as this:
=OR(ISNUMBER(FIND(Letters,A1)))
Where A1 is the subject cell.
This will be case sensitive. If you don't want it to be case sensitive then use the SEARCH() function instead of FIND().
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