I didn't check it, but hopefully it will work properly:
Code:
Sub Macro()
Dim oRng As range
Set oRng = ActiveDocument.StoryRanges(1)
oRng.Find.ClearFormatting
With oRng.Find.Font
.Superscript = True
End With
oRng.Find.Replacement.ClearFormatting
With oRng.Find.Replacement.Font
.Superscript = False
End With
oRng.Find.Execute Replace:=wdReplaceAll
set oRng = Nothing
End Sub