Similar to Ann, I've encountered the situation quite a lot over the past six months or so whereby the Ctrl-C for copy gets disabled more often than I would like. Often this is predictable, for instance while a macro is paused or I have a dialog hidden behind a window. I am not sure why it has become waaay more common recently but it is certainly annoying.

Right clicking to copy at least gives me a visual clue as to what is going on.

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Andrew Lockton
Chrysalis Design, Melbourne Australia