Hi David,
I take it you're not trying to save to a PDF file of the same name & extension as one that is already open.
It's possible an app crash has left a file related to the PDF/XPS untility in a locked state or crrupted. In that case, uninstalling & reinstalling the add-in might resolve the problem.
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Cheers,
Paul Edstein
[Fmr MS MVP - Word]
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