Have you tried repairing the Office installation (via Windows Control Panel > Programs > Programs & Features > Microsoft Office (version) > Change > Repair)?
Since working in Safe mode seems OK, you may also have a rogue 3rd-party addin. You could try disabling all such addins, then re-enabling them one at a time until you find the culprit (which might take a while if Word continues to work for 24-36 hours). Once you identify the culprit, you can either uninstall or update it.
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Cheers,
Paul Edstein
[Fmr MS MVP - Word]
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