Thank you both for your help.
I've had to ammend the forumla slightly as I had to strip down both the spreadsheets in order to upload them (too big!).
This is the formula I now have:
=IF(ISNA(VLOOKUP(F6,[Picklist1.xls]Pick!$D$2:$H$493,1,FALSE))=TRUE,0,VLOOKUP(F6,[Picklist1.xls]Pick!$D$2:$H$493,4,FALSE))
Thanks again