If you look at heading 5.4 in this table of contents you see that the page number 8 did not fit on the end of the line so it's dropped below item 5.4
and looks a bit confusing. I think in this situation 'CRISPR/Cas9' should drop to the line below which should then fill with dots .........
with an '8' at the end. Is it possible to make that happen?