I have a widescreen 16:9 PowerPoint 2016 presentation. Looks fine on my 24" widescreen monitor but when I present it in Slideshow in a conference room 80" 16:9 monitor it shifts the heading text at top down slightly. Goes from centered in the red box to shifted downward. Not a huge amount, but its bugging me!
On 24" 16:9 screen:
On 80" 16:9 screen: